Analysis of urinary volatile organic compounds for prostate cancer diagnosis: A systematic review.

ABSTRACT:

Context

Prostate-specific antigen is non-specific for prostate cancer. This is improved by multiparametric MRI but a significant amount of indolent prostate cancer is detected by the current MRI pathway and data is emerging that clinically significant cancers maybe missed using a standard PSA threshold. Volatile organic compound (VOC) analysis may offer novel biomarkers for prostate cancer and clinically significant disease.

Objective

To perform a systematic review of the literature to evaluate the current evidence for the use of VOCs as novel biomarkers for prostate cancer and clinically significant prostate cancer.

Evidence acquisition

A systematic search of MEDLINE, Scopus, Web of Science and the Cochrane Library was undertaken by two independent reviewers and pape

SUBMITTER: Dawson J 

PROVIDER: S-EPMC11420098 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature