Long-term oncological outcomes after multimodal treatment for locally advanced prostate cancer.

ABSTRACT:

Objective

The aim of this study is to evaluate treatment patterns and long-term oncological outcomes of patients with locally advanced prostate cancer (LAPCa).

Patients and methods

This is a population-based study including LAPC (cT3-4, M0) patients from the Stockholm region (Sweden). A sub-analysis was performed in men treated with primary cystoprostatectomy or total pelvic exenteration (TPE) for cT4 prostate cancer (PCa).Cox regression was used to identify predictors of overall mortality (OM) and cancer-specific mortality (CSM). Biochemical progression-free survival (BPFS) and 90 days complications were reported for the radical surgery subgroup.

Results

We included 2921 patients with cT3(N = 2713) or cT4(N = 208), M0 PCa diagnosed between 2003 and 2019

SUBMITTER: Roldan FL 

PROVIDER: S-EPMC11420104 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature