Closed-loop oxygen usage during invasive mechanical ventilation of pediatric patients (CLOUDIMPP): a randomized controlled cross-over study.

ABSTRACT:

Background

The aim of this study is the evaluation of a closed-loop oxygen control system in pediatric patients undergoing invasive mechanical ventilation (IMV).

Methods

Cross-over, multicenter, randomized, single-blind clinical trial. Patients between the ages of 1 month and 18 years who were undergoing IMV therapy for acute hypoxemic respiratory failure (AHRF) were assigned at random to either begin with a 2-hour period of closed-loop oxygen control or manual oxygen titrations. By using closed-loop oxygen control, the patients' SpO₂ levels were maintained within a predetermined target range by the automated adjustment of the FiO₂. During the manual oxygen titration phase of the trial, healthcare professionals at the bedside made manual changes to the

SUBMITTER: Atakul G 

PROVIDER: S-EPMC11420134 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature