Hierarchical communities in the larval <i>Drosophila</i> connectome: Links to cellular annotations and network topology.

ABSTRACT: One of the longstanding aims of network neuroscience is to link a connectome's topological properties-i.e., features defined from connectivity alone-with an organism's neurobiology. One approach for doing so is to compare connectome properties with annotational maps. This type of analysis is popular at the meso-/macroscale, but is less common at the nano-scale, owing to a paucity of neuron-level connectome data. However, recent methodological advances have made possible the reconstruction of whole-brain connectomes at single-neuron resolution for a select set of organisms. These include the fruit fly, Drosophila melanogaster, and its developing larvae. In addition to fine-scale descriptions of connectivity, these datasets are accompanied by rich annotations. Here, we use a variant o

SUBMITTER: Betzel R 

PROVIDER: S-EPMC11420166 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature