Association of stress hormones and the risk of cardiovascular diseases systematic review and meta-analysis.

ABSTRACT:

Background

The roles of endogenous stress hormones (norepinephrine, epinephrine, and cortisol) in cardiovascular diseases have been discussed. However, the higher versus lower level of stress hormones in relation to cardiovascular risks remained uncertain.

Methods

We searched databases from their inception to 31, March 2023. We conducted a meta-analysis to estimate the effect of higher to lower level of stress hormones with random effect model. Subgroup and meta-regression analysis were done to clarify the heterogeneity.

Results

In total, 33 studies involving 43641 participants were included. With regard to cardiovascular disease risks, a higher risk for individuals with higher level of all stress hormones (risk ratio (RR), 1.63; 95 % Confidence intervals (CIs): 1.36,

SUBMITTER: Tsai SY 

PROVIDER: S-EPMC11420448 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature