Liver transplant recipients have worse metabolic body phenotype compared with matched non-transplant controls.

ABSTRACT:

Background and aim

Quantification of body compartments, particularly the interaction between adipose tissue and skeletal muscle, is emerging as novel a biomarker of metabolic health. The present study evaluated the impact of liver transplant (LT) on body compartments.

Methods

Totally 66 adult LT recipients were enrolled in whom body compartments including visceral adipose tissue (VAT), abdominal subcutaneous adipose tissue (ASAT), muscle fat infiltration (MFI), fat-free muscle volume (FFMV), and liver fat (LF) were quantified via whole body magnetic resonance imaging (MRI). To provide non-LT comparison, each LT recipient was matched to at least 150 non-LT controls for same sex, age, and body mass index (BMI) from the UK Biobank registry.

Results

LT recipients (vs</

SUBMITTER: Bhati C 

PROVIDER: S-EPMC11420625 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature