Alzheimer Dementia Among Individuals With Down Syndrome.

ABSTRACT:

Importance

With the advancement in administrative data as a research tool and the reliance on public health insurance for individuals with Down syndrome, population-level trends in Alzheimer dementia in this population are beginning to be understood.

Objective

To comprehensively describe the epidemiology of Alzheimer dementia in adults with Down syndrome in a full US Medicare and Medicaid sample.

Design, setting, and participants

This cohort study included 132 720 adults aged 18 years or older with Medicaid and/or Medicare claims data with an International Statistical Classification of Diseases and Related Health Problems code for Down syndrome. Data were collected from January 1, 2011, to December 31, 2019, and analyzed from August 2023 to May 2024.

Main outcomes

SUBMITTER: Rubenstein E 

PROVIDER: S-EPMC11420697 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature