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The relationship between changes in functional connectivity gradients and cognitive-emotional disorders in sudden sensorineural hearing loss.


ABSTRACT: Sudden sensorineural hearing loss, a prevalent emergency in otolaryngology, is known to potentially precipitate cognitive and emotional disorders in affected individuals. Extensive research has documented the phenomenon of cortical functional reorganization in patients with sudden sensorineural hearing loss. However, the potential link between this neural functional remodelling and cognitive-emotional disorders remains unclear. To investigate this issue, 30 bilateral sudden sensorineural hearing loss patients and 30 healthy adults were recruited for this study. We collected clinical data and resting-state functional magnetic resonance imaging data from the participants. Gradient mapping analysis was employed to calculate the first three gradients for each subject. Subsequently, gradient ch

SUBMITTER: Li B 

PROVIDER: S-EPMC11420982 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature