An eco-friendly smartphone based HPTLC method versus conventional densitometric one for determination of Naltrexone and Bupropion.

ABSTRACT: The rapid uprising technologies of smartphone applications and software introduced a new era for analytical detection techniques. It has transformed bench-top laboratory methods into simpler ones depending on cost-effective, portable, and widely accessible devices. In this work, two high performance thin layer chromatographic (HPTLC) methods were developed based on smartphone's camera detection and either ImageJ desktop software or Color-Picker smartphone's application as alternative techniques to conventional densitometric detection. A mixture of Naltrexone hydrochloride (NAL) and Bupropion hydrochloride (BUP) was chromatographed on HPTLC- plates using ethyl acetate, methanol, acetone, and glacial acetic acid (3:6:1:0.5, by volume) as a developing system. The developed plates were scanned

SUBMITTER: Moaaz EM 

PROVIDER: S-EPMC11421204 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature