Lens Thickness in Infants and Children with Cataracts.

ABSTRACT:

Purpose

The purpose of this study was to determine the association between lens thickness and cataract in participants aged 0 to 5 years.

Design

This was a prospective, multicenter, case-control study.

Participants

We enrolled 118 participants (171 eyes) aged 0 to 5 years, mean age 14.6 ± 17.0 months, range 0 to 60 months.

Methods

Lens thickness was measured on 342 ultrasound biomicroscopy (UBM) images.

Main outcome measures

Lens thickness; feasibility of lens thickness measurement from UBM images.

Results

The mean lens thickness among noncataracts was 3.60 ± 0.17 mm, compared with 3.16 ± 0.61 mm among cataracts (P < 0.0001). Lens thickness <3.5 mm was significantly associated with increased odds of cataract; adjusted odds ratio = 5.99 (95%

SUBMITTER: Wei L 

PROVIDER: S-EPMC11421318 | biostudies-literature | 2025 Jan-Feb

REPOSITORIES: biostudies-literature