Noninvasive quantification of cerebrovascular pressure changes using 4D Flow MRI.

ABSTRACT:

Purpose

Hemodynamic alterations are indicative of cerebrovascular disease. However, the narrow and tortuous cerebrovasculature complicates image-based assessment, especially when quantifying relative pressure. Here, we present a systematic evaluation of image-based cerebrovascular relative pressure mapping, investigating the accuracy of the routinely used reduced Bernoulli (RB), the extended unsteady Bernoulli (UB), and the full-field virtual work-energy relative pressure ( ν WERP) method.

Methods

Patient-specific in silico models were used to generate synthetic cerebrovascular 4D Flow MRI, with RB, UB, and ν WERP performance quantified as a function of spatiotemporal sampling and image noise. Cerebrovascular relative pressures were also derived in 4D Flow MRI from healthy v

SUBMITTER: Marlevi D 

PROVIDER: S-EPMC11421438 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature