Co-occurring conditions during pregnancy and hospitalizations in the first year postpartum among persons with opioid use disorder.

ABSTRACT:

Introduction

Pregnant persons with opioid use disorder (OUD) face a multitude of comorbid conditions that may increase the risk of adverse drug and health outcomes. This study characterizes typologies of comorbidities among pregnant persons with OUD and assesses the associations of these typologies with hospitalizations in the first year postpartum.

Methods

A cohort of pregnant persons with OUD at delivery in 2018 were identified in a Pennsylvania statewide hospital dataset (n = 2055). Latent class analysis assessed 12 comorbid conditions including substance use disorders (SUDs), mental health conditions, and infections. Multivariable logistic regressions examined the association between comorbidity classes and hospitalizations (all-cause, OUD-specific, SUD-related, mental h

SUBMITTER: Frankeberger J 

PROVIDER: S-EPMC11421478 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature