Vitamin A-containing dietary supplements from German and US online pharmacies: market and risk assessment.

ABSTRACT: Vitamin A supplements are used by many people, and the number of newly registered dietary supplements is continuously increasing. The preparations fall under food law and are not subject to the strict controls of pharmaceuticals. Risk indications and maximum quantity recommendations, e.g., from the Bundesinstitut für Risikobewertung (BfR) and the U.S. Food and Drug Administration (FDA) are not binding, which means that overdoses and potentially serious health problems can easily occur. The hepatotoxicity and teratogenicity of vitamin A are well documented, and other negative effects of high doses of vitamin A are also being discussed. Nevertheless, preparations with exorbitantly high doses are freely available for sale and unrestricted. In this study, 75 supplements containing vitamin A av

SUBMITTER: Rathmann AM 

PROVIDER: S-EPMC11422271 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature