Exploring the impact and influence of melanin on frequency-domain near-infrared spectroscopy measurements.

ABSTRACT:

Significance

Near-infrared spectroscopy (NIRS) is a non-invasive optical method that measures changes in hemoglobin concentration and oxygenation. The measured light intensity is susceptible to reduced signal quality due to the presence of melanin.

Aim

We quantify the influence of melanin concentration on NIRS measurements taken with a frequency-domain near-infrared spectroscopy system using 690 and 830 nm.

Approach

Using a forehead NIRS probe, we measured 35 healthy participants and investigated the correlation between melanin concentration indices, which were determined using a colorimeter, and several key metrics from the NIRS signal. These metrics include signal-to-noise ratio (SNR), two measurements of oxygen saturation (arterial oxygen saturation, SpO2 , and tis

SUBMITTER: Roy S 

PROVIDER: S-EPMC11423252 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature