Criticality and universality in neuronal cultures during "up" and "down" states.

ABSTRACT: The brain can be seen as a self-organized dynamical system that optimizes information processing and storage capabilities. This is supported by studies across scales, from small neuronal assemblies to the whole brain, where neuronal activity exhibits features typically associated with phase transitions in statistical physics. Such a critical state is characterized by the emergence of scale-free statistics as captured, for example, by the sizes and durations of activity avalanches corresponding to a cascading process of information flow. Another phenomenon observed during sleep, under anesthesia, and in in vitro cultures, is that cortical and hippocampal neuronal networks alternate between "up" and "down" states characterized by very distinct firing rates. Previous theoretical work h

SUBMITTER: Yaghoubi M 

PROVIDER: S-EPMC11423291 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature