The association between accelerated biological aging and the risk of osteoarthritis: a cross-sectional study.

ABSTRACT:

Background

Biological age (BA) offers an effective assessment of true aging state. The progression of Osteoarthritis (OA) is closely associated with an increase in chronological age, the correlation between BA and OA has not been fully elucidated.

Methods

This study analyzed data from the National Health and Nutrition Examination Survey (NHANES) 2005-2018. Thirteen commonly used clinical traits were employed to calculate two measures of BA: the Klemera-Doubal method age (KDM-Age) and phenotypic age (Pheno-Age). The residuals of the regression of these ages based on chronological age were calculated as KDM-Age or Pheno-Age acceleration, respectively. OA was determined through self-reported prior diagnoses. The prevalence of OA across different quartiles of BA was compared usi

SUBMITTER: He Q 

PROVIDER: S-EPMC11423293 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature