Executive Function and Impulsivity Predict Distinct Genetic Variance in Internalizing Problems, Externalizing Problems, Thought Disorders, and Compulsive Disorders: A Genomic Structural Equation Modeling Study.

ABSTRACT: Individual differences in self-control predict many health and life outcomes. Building on twin literature, we used genomic structural equation modeling to test the hypothesis that genetic influences on executive function and impulsivity predict independent variance in mental health and other outcomes. The impulsivity factor (comprising urgency, lack of premeditation, and other facets) was only modestly genetically correlated with low executive function (r_g =.13). Controlling for impulsivity, low executive function was genetically associated with increased internalizing (β_g =.15), externalizing (β_g =.13), thought disorders (β_g =.38), compulsive disorders (β_g =.22), and chronotype (β_g

SUBMITTER: Gustavson DE 

PROVIDER: S-EPMC11423426 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature