A multimodal approach to diagnosis of neuromuscular neosporosis in dogs.

ABSTRACT:

Background

Early diagnosis of neosporosis in dogs is challenging.

Objectives

To evaluate the feasibility of a compound multimodal testing approach for diagnosing in dogs neuromuscular and combined forms of neosporosis.

Animals

A total of 16 dogs diagnosed with solely neuromuscular neosporosis or with a combination of neuromuscular and central nervous system neosporosis.

Methods

Retrospective review of clinical signs, laboratory findings, treatment, and outcome with focus on the diagnostic utility of different tests. Development of a chromogenic in situ hybridization (ISH) assay for the identification of Neospora caninum in paraffin-embedded muscle samples.

Results

13/16 dogs had only neuromuscular signs of neosporosis, 3/16 had disease signs with concomi

SUBMITTER: Alf V 

PROVIDER: S-EPMC11423454 | biostudies-literature | 2024 Sep-Oct

REPOSITORIES: biostudies-literature