Evidence and potential mechanism of action of indigo naturalis and its active components in the treatment of psoriasis.

ABSTRACT:

Background

Indigo naturalis is effective against psoriasis. Indigo, indirubin and tryptanthrin, the main active components of indigo naturalis, have anti-inflammatory properties.

Objective

To evaluate the efficacy and safety of indigo naturalis and its active components in the treatment of psoriasis.

Methods

Seven databases were searched for studies of indigo naturalis and its active components for the treatment of psoriasis.

Results

The findings demonstrated a higher response rate in the Chinese herbal medicine (CHM) formula groups than in the control group for Psoriasis Area and Severity Index 60 (PASI60) (Rate difference [RD] = 0.22, p < .0001). Among all adverse events, only the incidence of gastrointestinal adverse reactions was higher in the CHM fo

SUBMITTER: Wang C 

PROVIDER: S-EPMC11423532 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature