Phase-resolved MRI for measurement of pulmonary perfusion and ventilation defects in comparison with dynamic contrast-enhanced MRI and ¹²⁹Xe MRI.

ABSTRACT:

Introduction

This meta-analysis aims to evaluate the agreement and correlation between phase-resolved functional lung MRI (PREFUL MRI) and dynamic contrast-enhanced (DCE) MRI in evaluating perfusion defect percentage (QDP), as well as the agreement between PREFUL MRI and ¹²⁹Xe MRI in assessing ventilation defect percentage (VDP).

Method

A systematic search was conducted in the Medline, Embase and Cochrane Library databases to identify relevant studies comparing QDP and VDP measured by DCE MRI and ¹²⁹Xe MRI compared with PREFUL MRI. Meta-analytical techniques were applied to calculate the pooled weighted bias, limits of agreement (LOA) and correlation coefficient. The publication bias was assessed using Egger's regression test, while heterogeneity was as

SUBMITTER: Ouyang T 

PROVIDER: S-EPMC11423719 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature