Real-world treatment patterns in patients with systemic lupus erythematosus: associations with comorbidities and damage.

ABSTRACT:

Objective

To assess treatment patterns and the association between long-term glucocorticoid (GC) and hydroxychloroquine (HCQ) use and damage accrual in patients with systemic lupus erythematosus (SLE).

Methods

A retrospective study including patients with SLE using the computerised database of a large health maintenance organisation. Patients were matched with subjects from the general population. Multivariable logistic regression models were used to assess the association between GC cumulative daily doses, HCQ and comorbidities: Osteoporosis, cardiovascular disease (CVD), hypertension and diabetes mellitus. Models were adjusted for age, sex, socioeconomic status, smoking, disease duration and HCQ use.

Results

A total of 1073 patients with SLE were included, 87.79% we

SUBMITTER: Eviatar T 

PROVIDER: S-EPMC11423723 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature