Macular exudate in idiopathic intracranial hypertension affects outer retina and visual acuity.

ABSTRACT:

Background

Optical coherence tomography (OCT) is suggested as a potential tool for retinal biomarkers in idiopathic intracranial hypertension (IIH). We explored how macular exudate (ME) affects retinal structure in IIH and investigated its relationship with their clinical features.

Methods

Patients diagnosed with IIH and matched controls were enrolled. ME detection was done on fundus photography; swept-source OCT was used to image and measure the retinal sublayer thicknesses, including the retinal nerve fibre layer, ganglion cell-inner plexiform layer (GCIPL), inner nuclear layer (INL) and outer retinal layer (ORL). IIH patients underwent lumbar puncture where intracranial pressure (ICP) was assessed.

Results

195 eyes from 98 IIH patients (42 eyes had ME) and 224 eyes

SUBMITTER: Cao L 

PROVIDER: S-EPMC11423724 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature