Clinical translation of noninvasive intracranial pressure sensing with diffuse correlation spectroscopy.

ABSTRACT:

Objective

Intracranial pressure (ICP) is an important therapeutic target in many critical neuropathologies. The current tools for ICP measurements are invasive; hence, these are only selectively applied in critical cases where the benefits surpass the risks. To address the need for low-risk ICP monitoring, the authors developed a noninvasive alternative.

Methods

The authors recently demonstrated noninvasive quantification of ICP in an animal model by using morphological analysis of microvascular cerebral blood flow (CBF) measured with diffuse correlation spectroscopy (DCS). The current prospective observational study expanded on this preclinical study by translating the method to pediatric patients. Here, the CBF features, along with mean arterial pressure (MAP) and heart ra

SUBMITTER: Tabassum S 

PROVIDER: S-EPMC11423936 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature