Improvement of esophageal cancer survival in Northeast Iran: A two-decade journey in a high-risk, low- resource region.

ABSTRACT:

Background and objective

Two decades ago, an international initiative (GEMINI) was launched in a high-risk, low-resource region in Northeast Iran, aiming to investigate incidence, etiology, early detection, and treatment of esophageal squamous cell carcinoma (ESCC). An earlier report from this area, highlighted poor ESCC survival rates, with a 5-year survival probability of 3.3% and the median survival time of 7 months. Our study assesses whether ESCC survival has improved since the implementation of the GEMINI initiative in this region.

Material and methods

490 adult patients with histologically-confirmed ESCC were recruited from the Atrak clinic, Golestan, Iran, between 2007 and 2018. At recruitment, information on demographics and various exposures were collected. Active

SUBMITTER: Nemati S 

PROVIDER: S-EPMC11423987 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature