Developmental differences in canonical cortical networks: Insights from microstructure-informed tractography.

ABSTRACT: In response to a growing interest in refining brain connectivity assessments, this study focuses on integrating white matter fiber-specific microstructural properties into structural connectomes. Spanning ages 8-19 years in a developmental sample, it explores age-related patterns of microstructure-informed network properties at both local and global scales. First, the diffusion-weighted signal fraction associated with each tractography-reconstructed streamline was constructed. Subsequently, the convex optimization modeling for microstructure-informed tractography (COMMIT) approach was employed to generate microstructure-informed connectomes from diffusion MRI data. To complete the investigation, network characteristics within eight functionally defined networks (visual, somatomotor, dorsal

SUBMITTER: Genc S 

PROVIDER: S-EPMC11424039 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature