Pulmonary artery denervation versus conventional therapies for PAH: a systematic review and updated network meta-analysis.

ABSTRACT:

Aims

A recent guideline presented by the ESC Congress in 2022 had indicated a novel therapy targeted at pulmonary artery hypertension, known as pulmonary artery denervation (PADN), which get inspired from a laboratorial trial that could lowering the pulmonary artery pressure through the intervention on the animals. Our aim is to conduct a network meta-analysis to compare the efficacy and safety of PADN from six aspects with the current conventional therapies.

Methods and results

According to the PRISMA guidance, databases including Ovid, ClinicalTrials.gov, Medline, Embase, and PubMed were searched from inception to 22 August 2023, along with a full assessment of the previous five meta-analyses. Data were extracted and curated for Bayesian network meta-analysis. The primary

SUBMITTER: Wu X 

PROVIDER: S-EPMC11424296 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature