Association between biomarkers of zinc and copper status and heart failure: a meta-analysis.

ABSTRACT:

Aims

Previous studies have investigated the relationship between heart failure (HF) and levels of zinc and copper, but conflicting results have been reported. This meta-analysis aims to clarify the role of zinc and copper in HF progression by examining the associations between HF and concentrations of these minerals.

Methods and results

We utilized STATA 12.0 software to calculate the standard mean difference (SMD) and 95% confidence interval (CI) for serum zinc and copper levels in patients with HF compared with healthy controls (HCs). The meta-analysis indicated a lower serum zinc level in patients with HF compared with HCs, using a random effects model (SMD = -0.77; 95% CI: -1.01, -0.54; I² = 61.9%, the P-value for Q test = 0.002). Additionally, the meta-analys

SUBMITTER: Liu R 

PROVIDER: S-EPMC11424300 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature