Renal dysfunction is a time-varying risk predictor of sudden cardiac death in heart failure.

ABSTRACT:

Aims

Sudden cardiac death (SCD) is a common mode of death in patients with congestive heart failure (CHF). Implantable cardioverter defibrillator (ICD) implantation is established treatment for SCD prevention, but current eligibility criteria based on left ventricular ejection fraction (LVEF) and New York Heart Association (NYHA) functional class may be due for reconsideration given the increasing effectiveness of pharmacological therapy. We sought to reconsider the risk stratification of SCD in patients with symptomatic CHF.

Methods

In total, 1,676 consecutive patients (74 ± 13 years old; 56% male) with NYHA class II or III CHF between 2008 and 2015 were enrolled for this prospective study. The endpoint was SCD.

Results

During a median (interquartile range) follow-up

SUBMITTER: Sobue Y 

PROVIDER: S-EPMC11424313 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature