Clinicopathological features, treatment patterns, and survival outcomes among Syrian patients with advanced breast cancer.

ABSTRACT:

Background

Advanced breast cancer (ABC) is a heterogeneous disease with varied prognoses, that is affected by many clinicopathological features. This study aimed to investigate the clinicopathological characteristics, first-line treatment (FLx), and prognostic impact of these features on survival among Syrian patients with ABC.

Materials and methods

This retrospective cohort study included patients with ABC. The association of clinicopathological factors with survival was assessed using Kaplan-Meier curves and the log-rank test, as well as the Cox proportional hazards regression model to calculate the hazard ratio (HaR).

Results

A total of 423 patients with ABC were included in the study, with a median age (range) of 47 years (23-82). 83% of metastases were metachrono

SUBMITTER: Muhammad M 

PROVIDER: S-EPMC11424526 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature