Research hotspots and trends of epigenetic therapy in oncology: a bibliometric analysis from 2004 to 2023.

ABSTRACT:

Background

Epigenetics denotes heritable alterations in gene expression patterns independent of changes in DNA sequence. Epigenetic therapy seeks to reprogram malignant cells to a normal phenotype and has been extensively investigated in oncology. This study conducts a bibliometric analysis of epigenetic therapy in cancer, providing a comprehensive overview of current research, identifying trends, and highlighting key areas of investigation.

Methods

Publications concerning epigenetic inhibitors in cancer spanning 2004 to 2023 were retrieved from the Web of Science Core Collection (WoSCC). Co-occurrence analysis using VOSviewer assessed current status and focal points. Evolutionary trends and bursts in the knowledge domain were analyzed using CiteSpace. Bibliometrix facilitat

SUBMITTER: Li S 

PROVIDER: S-EPMC11424529 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature