Whole-genome comparison using complete genomes from Campylobacter fetus strains revealed single nucleotide polymorphisms on non-genomic islands for subspecies differentiation.

ABSTRACT:

Introduction

Bovine Genital Campylobacteriosis (BGC), caused by Campylobacter fetus subsp. venerealis, is a sexually transmitted bacterium that significantly impacts cattle reproductive performance. However, current detection methods lack consistency and reliability due to the close genetic similarity between C. fetus subsp. venerealis and C. fetus subsp. fetus. Therefore, this study aimed to utilize complete genome analysis to distinguish genetic features between C. fetus subsp. venerealis and other subspecies, thereby enhancing BGC detection for routine screening and epidemiological studies.

Methods and results

This study reported the complete genomes of four C. fetus subsp. fetus and five C. fetus subsp. venerealis, sequenced usin

SUBMITTER: Ong CT 

PROVIDER: S-EPMC11424552 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature