Poor sleep quality, dementia status and their association with all-cause mortality among older US adults.

ABSTRACT:

Background

Evidence points to associations between sleep quality, dementia, and mortality. We examined whether poor sleep quality mediated or moderated the association between dementia and mortality risk among older US adults and vice versa, and whether these associations differed by sex and by race.

Methods

The study investigated bi-directional associations between sleep quality, dementia and mortality in older US adults using data from the Health and Retirement Study (N = 6,991, mean age = 78.1y, follow-up: 2006-2020, number of deaths = 4,938). It tested interactions and mediating effects, using Cox proportional hazards models and four-way decomposition models.

Results

Poor sleep quality was associated with increased mortality risk, particularly among male an

SUBMITTER: Beydoun MA 

PROVIDER: S-EPMC11424588 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature