Moderators of exercise effects on self-reported cognitive functioning in cancer survivors: an individual participant data meta-analysis.

ABSTRACT:

Purpose

This individual participant data meta-analysis (IPD-MA) assesses exercise effects on self-reported cognitive functioning (CF) and investigates whether effects differ by patient-, intervention-, and exercise-related characteristics.

Methods

IPD from 16 exercise RCTs, including 1987 patients across multiple types of non-metastatic cancer, was pooled. A one-stage IPD-MA using linear mixed-effect models was performed to assess exercise effects on self-reported CF (z-score) and to identify whether the effect was moderated by sociodemographic, clinical, intervention- and exercise-related characteristics, or fatigue, depression, anxiety, and self-reported CF levels at start of the intervention (i.e., baseline). Models were adjusted for baseline CF and included a random inte

SUBMITTER: Hiensch AE 

PROVIDER: S-EPMC11424665 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature