Estimating Costs Associated with Disease Model States Using Generalized Linear Models: A Tutorial.

ABSTRACT: Estimates of costs associated with disease states are required to inform decision analytic disease models to evaluate interventions that modify disease trajectory. Increasingly, decision analytic models are developed using patient-level data with a focus on heterogeneity between patients, and there is a demand for costs informing such models to reflect individual patient costs. Statistical models of health care costs need to recognize the specific features of costs data which typically include a large number of zero observations for non-users, and a skewed and heavy right-hand tailed distribution due to a small number of heavy healthcare users. Different methods are available for modelling costs, such as generalized linear models (GLMs), extended estimating equations and latent class appro

SUBMITTER: Zhou J 

PROVIDER: S-EPMC11424740 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature