Screening Familial Risk for Hereditary Breast and Ovarian Cancer.

ABSTRACT:

Importance

Most patients with pathogenic or likely pathogenic (P/LP) variants for breast cancer have not undergone genetic testing.

Objective

To identify patients meeting family history criteria for genetic testing in the electronic health record (EHR).

Design, setting, and participants

This study included both cross-sectional (observation date, February 1, 2024) and retrospective cohort (observation period, January 1, 2018, to February 1, 2024) analyses. Participants included patients aged 18 to 79 years enrolled in Renown Health, a large health system in Northern Nevada. Genotype was known for 38 003 patients enrolled in Healthy Nevada Project (HNP), a population genomics study.

Exposure

An EHR indicating that a patient is positive for criteria according to t

SUBMITTER: Kiser D 

PROVIDER: S-EPMC11425146 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature