Myocardial Scarring and Sudden Cardiac Death in Young Patients With Hypertrophic Cardiomyopathy: A Multicenter Cohort Study.

ABSTRACT:

Importance

The ability to predict sudden cardiac death (SCD) in children and adolescents with hypertrophic cardiomyopathy (HCM) is currently inadequate. Late gadolinium enhancement (LGE) by cardiovascular magnetic resonance (CMR) imaging is associated with SCD events in adults with HCM.

Objective

To examine the prognostic significance of LGE in patients with HCM who are younger than 21 years.

Design, setting, and participants

This multicenter, retrospective cohort study was conducted from April 8, 2015, to September 12, 2022, in patients with HCM who were younger than 21 years and had undergone CMR imaging across multiple sites in the US, Europe, and South America. Observers of CMR studies were masked toward outcomes and demographic characteristics.

Exposure

Na

SUBMITTER: Chan RH 

PROVIDER: S-EPMC11425184 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature