Home- vs Office-Based Narrowband UV-B Phototherapy for Patients With Psoriasis: The LITE Randomized Clinical Trial.

ABSTRACT:

Importance

Office-based phototherapy is cost-effective for psoriasis but difficult to access. Home-based phototherapy is patient preferred but has limited clinical data, particularly in patients with darker skin.

Objective

To compare the effectiveness of home- vs office-based narrowband UV-B phototherapy for psoriasis.

Design, setting, and participants

The Light Treatment Effectiveness study was an investigator-initiated, pragmatic, open-label, parallel-group, multicenter, noninferiority randomized clinical trial embedded in routine care at 42 academic and private clinical dermatology practices in the US. Enrollment occurred from March 1, 2019, to December 4, 2023, with follow-up through June 2024. Participants were 12 years and older with plaque or guttate psoriasis

SUBMITTER: Gelfand JM 

PROVIDER: S-EPMC11425190 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature