Red Blood Cell Transfusion for Incidence of Retinopathy of Prematurity: Prospective Multicenter Cohort Study.

ABSTRACT:

Background

Retinopathy of prematurity (ROP) is a leading cause of visual impairment and blindness in preterm infants.

Objective

This study sought to investigate the association between red blood cell (RBC) transfusion and ROP in very preterm infants (VPIs) to inform clinical strategies for ROP prevention and treatment.

Methods

We designed a prospective multicenter cohort study that included VPIs and follow-up data from January 2017 to December 2022 at 3 neonatal clinical medicine centers. They were categorized into a transfusion group (infants who received an RBC transfusion within 4 wk) and a nontransfusion group. The relationship between RBC transfusion and ROP incidence was assessed using binary logistic regression, with subgroup analyses based on gestational age,

SUBMITTER: Wang X 

PROVIDER: S-EPMC11425406 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature