Dynamic assessment of left ventricular coupling and myocardial reserve in patients with cardiogenic shock.

ABSTRACT:

Aims

Pulmonary artery catheter haemodynamics are associated with improved survival in cardiogenic shock (CS). We investigated the utility of aortic pulsatility index (API) and cardiac power output (CPO) as surrogates for left ventricular (LV) coupling and myocardial reserve, respectively, in patients with CS undergoing dynamic assessment after a milrinone bolus.

Methods and results

Patients with SCAI Stage C CS underwent a milrinone drug study (50 mcg/kg bolus infused over 10 min) to assess inotropic response. Haemodynamic measurements were obtained at baseline and following the bolus. Aortic pulsatility index and CPO were used to risk-stratify patients with the incidence of LV assist device (LVAD), orthotopic heart transplantation (OHT), or death at 1 year as the primary co

SUBMITTER: Kanelidis AJ 

PROVIDER: S-EPMC11425697 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature