Synergistic Role of the AuAg-Fe₃O₄ Nanoenzyme for Ultrasensitive Immunoassay of Dengue Virus.

ABSTRACT: A combination of magnetic and noble metal nanoparticles (NPs) has recently emerged as a potential substance for rapid and sensitive immunosorbent assays. However, to make the assay an alternative method for Enzyme-linked immunosorbent assay, the individual role of each nanoparticle must be explored properly. In this work, an immunoassay has been proposed using two antibody-conjugated iron oxide nanoparticles (Fe₃O₄NPs) and gold-silver bimetallic nanoparticles (AuAgNPs) to enhance the sensitivity of virus detection by colorimetric TMB/H₂O₂ signal amplification. A synergistic effect is monitored between Fe₃O₄NPs and AuAgNPs, which is explored for colorimetric virus detection. The sensor exploits the synergistic effect between

SUBMITTER: Dasgupta U 

PROVIDER: S-EPMC11425808 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature