Effect of volatile anaesthetic agents on intracranial pressure, cerebrovascular flow and autoregulation: a protocol for a systematic review and meta-analysis.

ABSTRACT:

Introduction

The use of volatile anaesthetic agents for the sedation of patients requiring critical care treatment offers several theoretical advantages over intravenous sedation, which may be of benefit in neurocritical care. However, there are concerns that they may increase intracranial pressure. The objective of this systematic review is to assess whether, and if so, to what extent volatile anaesthetic agents affect intracranial pressure, cerebral blood flow (CBF), cerebral oximetry and cerebrovascular autoregulation. If sufficient data exist, subgroup analyses will be conducted in traumatic brain injury and decompressive craniectomy patients.

Methods and analysis

A database search of PubMed, Medline (including Medline plus), CINAHL (including CINAHL Plus), Embase databa

SUBMITTER: Taylor B 

PROVIDER: S-EPMC11425943 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature