Neonatal encephalopathy: a systematic review of reported treatment outcomes.

ABSTRACT:

Background

Neonatal encephalopathy (NE) is a multi-organ condition potentially leading to death or long-term neurodisability. Therapeutic hypothermia is the standard treatment for NE; however, long-term impairments remain common. Studies of new treatments for NE often measure and report different outcomes. Core outcome sets (COSs), a minimum set of outcomes to be measured and reported in all studies for a condition, address this problem. This paper aimed to identify outcomes reported (primary, secondary, adverse events and other reported outcomes) in (1) randomised trials and (2) systematic reviews of randomised trials of interventions for the treatment of NE in the process of developing a COS for interventions for the treatment of NE.

Methods

We completed a systematic searc

SUBMITTER: Quirke F 

PROVIDER: S-EPMC11425948 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature