Development and validation of the Florey Dementia Risk Score web-based tool to screen for Alzheimer's disease in primary care.

ABSTRACT:

Background

It is estimated that ∼60% of people with Alzheimer's disease (AD) are undetected or undiagnosed, with higher rates of underdiagnosis in low-to middle-income areas with limited medical resources. To promote health equity, we have developed a web-based tool that utilizes easy-to-collect clinical data to enhance AD detection rate in primary care settings.

Methods

This study was leveraged on the data collected from participants of the Australian Imaging, Biomarker & Lifestyle (AIBL) study and the Religious Orders Study and Memory and Aging Project (ROSMAP). The study included three phases: (1) constructing and evaluating a model on retrospective cohort data (1407 AIBL participants), (2) performing simulated trials to assess model accuracy (30 AIBL participants) and mi

SUBMITTER: Pan Y 

PROVIDER: S-EPMC11426130 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature