Association between human papillomavirus and preterm delivery: A systematic review and meta-analysis.

ABSTRACT:

Introduction

The lifetime prevalence of human papillomavirus infection (HPV) is estimated to be around 80% and it is the most common sexually transmitted infection. Despite being well known for its oncologic relevance, it has been associated with adverse pregnancy outcomes, though available evidence is contradicting. Previous meta-analyses involved articles which based HPV infection on Pap smear results, leading to a significant source of bias. Therefore, we aimed to assess the burden of genetically proven HPV infection on adverse pregnancy outcomes.

Material and methods

In our meta-analysis, pregnant women tested for HPV DNA were only considered eligible. We conducted a systematic search in three major databases (PubMed, Embase, and CENTRAL) on September 22, 2023. Cohort, c

SUBMITTER: Kovacs D 

PROVIDER: S-EPMC11426213 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature