Endometriosis and Sjogren's syndrome: Bidirectional associations in population-based 15-year retrospective cohorts.

ABSTRACT:

Introduction

Primary Sjögren's syndrome (pSS) is a chronic autoimmune disorder affecting salivary and lacrimal glands, while endometriosis involves uterine-like tissue growth outside the uterus, causing pelvic pain and infertility. Investigating their intricate relationship using real-world data is crucial due to limited research on their connection.

Material and methods

This population-based cohort study included patients with endometriosis and controls without endometriosis. Propensity score matching was used to balance baseline differences in demographic and clinic characteristics between the two groups. Cox proportional hazards model were used to estimate the effect of endometriosis on the risk of new-onset pSS over time. A symmetrical cohort study, including patients wi

SUBMITTER: Ma KS 

PROVIDER: S-EPMC11426214 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature