Negative prognostic impact of tumor deposits in stage III colorectal cancer patients.

ABSTRACT:

Background

The prognostic value of tumor deposits (TDs) in stage III colorectal cancer (CRC) patients is poorly described based on the current tumor node metastasis (TNM) stage system.

Materials and methods

Based on the data from the Surveillance, Epidemiology, and End Result (SEER) database between 2010 to 2020 and local hospital between 2006 to 2022, the clinicopathological features of stage III CRC patients with TDs were screened by Chi-square test. Kaplan-Meier curves were performed to describe the significant difference in overall survival (OS) among the different groups, and log-rank tests were used to compare the cumulative survival distributions.

Result

Patients with TDs exhibited more aggressive tumors, characterized by advanced T staging (T3&T4), N staging (

SUBMITTER: Ma T 

PROVIDER: S-EPMC11426431 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature