Aspirin reduces the mortality risk of patients with community-acquired pneumonia: a retrospective propensity-matched analysis of the MIMIC-IV database.

ABSTRACT:

Background

Community-acquired pneumonia (CAP) is a common infectious disease characterized by inflammation of the lung parenchyma in individuals who have not recently been hospitalized. It remains a significant cause of morbidity and mortality worldwide. Aspirin is a widely used drug, often administered to CAP patients. However, the benefits of aspirin remain controversial.

Objective

We sought to determine whether aspirin treatment has a protective effect on the outcomes of CAP patients.

Methods

We selected patients with CAP from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. Propensity score matching (PSM) balanced baseline differences. A multivariate Cox regression model assessed the relationship between aspirin treatment and 28-day mortalit

SUBMITTER: Wang G 

PROVIDER: S-EPMC11427301 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature