Pharyngeal Pumping Assay for Quantifying Feeding Behavior in <i>Caenorhabditis elegans</i>.

ABSTRACT: C. elegans is a well-established nematode model organism, with 83% of its genes conserved in humans with translation potential. C. elegans is translucent, with clearly defined cellular organization, and robustly identifiable under a microscope, being an excellent model for studying feeding behavior. Its neuromuscular pharyngeal pump undergoes a pumping motion that can be quantified to study feeding behavior at specific treatment conditions and in genetically modified worms. Understanding the evolutionarily conserved feeding behaviors and regulatory signals is vital, as unhealthy eating habits increase the risk of associated diseases. The current protocol was developed to identify and study evolutionary conserved signals regulating feeding behavior. The protocol described here is ver

SUBMITTER: Shanmugam MM 

PROVIDER: S-EPMC11427329 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature