The role of chloroplast SRP54 domains and its C-terminal tail region in post- and co-translational protein transport in vivo.

ABSTRACT: In the chloroplast, the 54 kDa subunit of the signal recognition particle (cpSRP54) is involved in the post-translational transport of the light-harvesting chlorophyll a/b-binding proteins (LHCPs) and the co-translational transport of plastid-encoded subunits of the photosynthetic complexes to the thylakoid membrane. It forms a high-affinity complex with plastid-specific cpSRP43 for post-translational transport, while a ribosome-associated pool coordinates its co-translational function. CpSRP54 constitutes a conserved multidomain protein, comprising a GTPase (NG) and a methionine-rich (M) domain linked by a flexible region. It is further characterized by a plastid-specific C-terminal tail region containing the cpSRP43-binding motif. To characterize the physiological role of the various reg

SUBMITTER: Bischoff A 

PROVIDER: S-EPMC11427828 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature