Near-Infrared Autofluorescence Signatures of Single- vs Multigland Disease in Primary Hyperparathyroidism.

ABSTRACT:

Importance

The success of parathyroidectomy depends on accurate intraoperative localization and identification of all diseased glands in parathyroid exploration based on surgeon expertise to prevent persistent hyperparathyroidism. Near-infrared autofluorescence (NIRAF) imaging has recently emerged as a promising adjunctive intraoperative tool for localizing parathyroid glands; however, its potential utility in the assessment of parathyroid glands has yet to be established.

Objective

To analyze the differences in NIRAF signatures of parathyroid glands in single vs multiple glands in primary hyperparathyroidism (pHPT).

Design, setting, and participants

This prospective diagnostic study analyzed in vivo NIRAF images of parathyroid glands obtained during parathyroidectomi

SUBMITTER: Akgun E 

PROVIDER: S-EPMC11428033 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature